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  • John Edwards 'not guilty' on one count; mistrial declared on remaining charges

    The jury delivered a unanimous verdict on one of the six felony counts and found Edwards not guilty of receiving illegal campaign contributions from heiress Rachel 'Bunny' Mellon. The judge declared a mistrial on the five other counts. Edwards later told reporters that he knew he had not done anything illegal but that he was accountable for his behavior. NBC's Lisa Myers reports.

    Updated at 4:34 p.m. ET -- Capping a day of dramatic turnarounds, the jury in the campaign finance trial of former presidential candidate John Edwards found him not guilty on Thursday on one count of accepting illegal campaign contributions and said it was deadlocked on the remaining five charges.

    U.S. District Judge Catherine Eagles then declared a mistrial on the remaining charges. It was not immediately clear if prosecutors intend to seek a retrial on those charges.

    In a statement outside the federal courthouse in Greensboro, N.C., Edwards acknowledged that he had behaved poorly, but said he had not acted illegally.

    Read Thursday's court transcript

    “I want to make sure that everyone hears from me … that while I don’t believe I did anything illegal,  I did an awful, awful lot that was wrong and there is no one else responsible for my sins,” said Edwards, who did not testify at the trial and took no questions.


    The count on which the jury reached a "not guilty" verdict involved contributions from Edwards' contributor Rachel "Bunny" Mellon.

    NBC station WNCN of Raleigh, N.C., reported that when the decision came, Edwards closed his eyes, rubbed his face and smiled at his daughter, Cate. He then hugged his daughter and his elderly parents while whispering to them, "I told you this would be OK," WCNC reported. Earlier, the jury of eight men and four women told Eagles that it had reached a verdict on all six felony accounts against Edwards. But after the jury returned to the courtroom, the foreperson stated that jurors had reached a unanimous decision on only one count. Eagles then sent them back to the jury room to resume deliberations.

    The charges against Edwards, 58, arose while he was in the midst of the 2008 race for the Democratic presidential nomination, and were focused on about $1 million in donations from two wealthy donors, Fred Baron and Mellon, a billionnaire banking heiress. The money was used to support and hide Edwards' pregnant mistress, Rielle Hunter.

    NBC News' Gabe Gutierrez reports on John Edwards' campaign finance trial after the jury found him not guilty on one count. The judge declared a mistrial on the remaining five counts. NBC News' Pete Williams, Savannah Guthrie and former prosecutor John Q. Kelly provide analysis on the case.

    Prosecutors argued that the money amounted to illegal and unreported campaign contributions at a time when federal donations were capped at $2,300; the defense said the money was a "gift" intended to allow Edwards to hide the affair from his ailing wife, Elizabeth, and the public. Elizabeth Edwards, who had previously been diagnosed with breast cancer, separated from John Edwards in early 2010 and died later that year.

    If found guilty of all six counts, Edwards could have faced up to 30 years in prison and a $1.5 million fine.  Each individual count carries a maximum sentence of 5 years and a fine of up to $250,000.

    Attorneys for Edwards, a former U.S. senator from North Carolina and the 2004 Democratic vice presidential nominee, and prosecutors alike painted him as a liar and a bad husband. Where they differed was whether the scheme to hide his affair amounted to a crime.

    The jurors were charged with deciding if Edwards "knowingly and willfully" violated a 1971 campaign finance law by orchestrating the scheme to support and hide Hunter.

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    Former Democratic presidential candidate John Edwards has faced public and private challenges throughout his life and career.

    Prosecutors alleged in their closing arguments that Edwards manipulated the campaign finance system to conceal the affair with Hunter, a videographer on his 2008 presidential campaign staff.

    He "clearly knew the law and decided to violate it in order to salvage his campaign," Assistant U.S. Attorney Robert Higdon said, accusing Edwards of cynically seeking to "keep her quiet" until the election was over "and his wife (had) passed away."

    Lead defense attorney Abbe Lowell admitted in his closing arguments that Edwards had committed many "moral wrongs," but he insisted that none of the misdeeds was "a legal one."

    "John's conduct is shameful, but it's human," Lowell told the jury.

    Letters and other notes from Mellon appeared to be crucial to the jurors' deliberations — from their first day of discussions, they requested a stream of exhibits related to the nearly $750,000 she contributed.

    Mellon, who is 101 years old, didn't testify during the trial, but her attorney and financial adviser, Alex Forger, offered extensive testimony that Mellon knew that her donations were intended to fund the "Hunter problem" and weren't given as campaign contributions.

    A possible turning point came in mid-May, when Judge Eagles barred most of the defense's planned testimony from current and former members of the Federal Election Commission about a federal audit that concluded that the money didn't amount to campaign contributions subject to federal regulation.

    Eagles ruled that evidence about the FEC audit was inadmissible because it couldn't be determined exactly what the commission knew or was told at the time.

    NBC's Savannah Guthrie examines how the legal terrain of political campaigns has changed since John Edwards ran for president in 2008.

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  • NBC-Marist polls: Obama, Romney deadlocked in three key states

    Now that Mitt Romney is the official GOP presidential nominee, President Obama placed a call to the former governor to congratulate him. Meanwhile both campaigns have already spent a combined $85 million on TV ads. NBC's Chuck Todd reports.

    President Barack Obama and presumptive Republican nominee Mitt Romney are deadlocked in three key presidential battleground states, according to a new round of NBC-Marist polls.

    In Iowa, the two rivals are tied at 44 percent among registered voters, including those who are undecided but leaning toward a candidate. Ten percent of voters in the Hawkeye State are completely undecided.

    Read the full Iowa poll


    In Colorado, Obama gets support from 46 percent of registered voters, while Romney gets 45 percent.

    Read the full Colorado poll

    And in Nevada, the president is at 48 percent and Romney is at 46 percent.

    Read the full Nevada poll

    These three states are all battlegrounds that Obama carried in 2008, but George W. Bush won in 2004.

    “These are very, very competitive states,” says Lee Miringoff, director of the Marist College Institute for Public Opinion, which conducted these polls. “Everything is close.”

    Results from NBC-Marist polling in three other battleground states released last week – Florida, Ohio and Virginia – showed Obama with narrow leads in each state.

    Optimism, pessimism and enthusiasm
    In Colorado, Iowa and Nevada, a more optimistic attitude about the U.S. economy is working in Obama’s favor. Majorities in each of the three states believe the worst is behind us, rather than yet to come.

    In addition, majorities in these states say that the president mostly inherited the current economic conditions. 

    David Axelrod, a senior adviser for President Obama's re-election campaign, speaks with TODAY's Matt Lauer about the President's strategies for taking on the battleground states and rekindling the enthusiasm from 2008.

    But what seems to be hurting Obama – and helping Romney – is a sense that the nation is on the wrong track, with 54 percent in Iowa, 55 percent in Nevada and 56 percent in Colorado sharing that belief.

    First Thoughts: Still fighting on GOP turf

    Asked which candidate would do a better job on the economy, respondents in Colorado (45 percent to 42 percent) and Iowa (46 percent to 41 percent) picked Romney over Obama. But the two men were tied in Nevada (44 percent to 44 percent). 

    What’s more, Romney leads Obama in Colorado and Iowa among those expressing a high level of enthusiasm, while the president leads among those voters in Nevada.

    Obama’s approval rating, Nevada’s Senate race
    The NBC-Marist poll also shows that Obama’s approval rating is above water in Iowa (46 percent approve, 45 percent disapprove), and it’s underwater in Colorado (45 percent to 49 percent) and Nevada (46 percent to 47 percent)

    And in Nevada’s competitive Senate contest, the survey finds incumbent Republican Sen. Dean Heller in a tight race with Democrat Shelley Berkley, with Heller getting 46 percent among registered voters and Berkley getting 44 percent.

    President Obama phones Mitt Romney to congratulate him for locking up the GOP nomination. NBC's Steve Handelsman reports.

    These NBC-Marist polls were conducted May 22-24 by landline and cell phone of 1,030 registered voters in Colorado, 1,106 registered voters in Iowa and 1,040 registered voters in Nevada. The margin of error in all three surveys is plus-minus 3.0 percentage points.

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  • Liberia's Charles Taylor jailed for 50 years for war crimes

     

    What we're following: 

    - Romney wins Texas GOP primary and secures delegates to win nomination

    - Liberia's Charles Taylor jailed for 50 years for war crimes 

    - Survivor pulled from rubble 12 hours after Italy quake

    And did you see...

    - Folk musician Doc Watson dies at 89

    - Virginia girl is youngest ever in National Spelling Bee

    - Apple CEO wants to make more products in the U.S.

     

     


     

  • Avoiding height loss as you age

    Doing weight-bearing exercises will keep bones strong, and prevent age-related height loss caused by bone-thinning. NBC's Dr. Nancy Snyderman reports.

    By Joyce Ho and Dr. Nancy Snyderman
    NBC News 

    It may be common knowledge that people tend to “shrink” as they age, but did you know that you can take simple, preventative steps to retain your height? 

    The average height loss in a person’s lifetime is estimated to be around one to three inches, or about half an inch every decade after age 40. Why? The vertebral bones that make up our spinal column are separated by gel-like disks. As we age, these disks get flatter, so our spinal column shrinks. Our vertebra also loses bone density as we age, making them thinner. The end result is a stooped spine. And it's not just hazardous to your posture -- Harvard researchers recently found that height loss, a commonly seen by-product of age-related bone thinning, is a predictor of future risk of hip fractures. 

    Tonight on “NBC Nightly News,” Dr. Nancy Snyderman offered tips on how to keep standing tall. Here are several ways to keep yourself healthy. 

    • Don’t drink excessively 
      Alcohol tampers with calcium levels in the body as well as hormone levels that affect bone density, damaging your bones. It also puts you at higher risk for falls and bone fractures.
    • Don’t smoke
      Smoking is a risk factor for bone loss, and the longer you smoke, the greater risk you have of bone fractures. Studies show that even exposure to secondhand smoke at an early age could contribute to bone loss. Prevent weak bones by quitting smoking.
    • Prevent falls
      Take preventative measures such as installing bars in the bathtub, buying shoes with tight gripping soles, and avoiding walking on slippery surfaces when it rains or snows.
    • Exercise daily to strengthen core muscles
      Exercise is always good for your health, but in this case, it is very important in keeping your bones and muscles strong for proper back and head support. Specific types of weight-bearing exercise where you work against gravity are good for preventing height loss such as walking, jogging or climbing stairs. Exercises such as swimming, running on the elliptical, and bicycling are not included in this class of physical activity.
    • Get a healthy dose of calcium and vitamin D
      Calcium and vitamin D are necessary for bone formation. The recommended daily intake for people before age 50 is 1,000  mg of calcium a day. For postmenopausal women and men over age 65, it's 1200 to 1500 mg of calcium a day and 400 to 800 international units of vitamin D everyday. Talk to your doctor about the best ways to get an adequate amount of these nutrients, either through your diet, supplements, or sun exposure. High calcium foods include tofu, yogurt, ice cream, cheese, and leafy green vegetables.

     


     

  • At National Parks, where are all the young people?

    The average age of visitors has skyrocketed over the past few decades, and some fear the future of these national treasures could be in jeopardy. NBC's Gabe Gutierrez reports.

    By Gabe Gutierrez, NBC News correspondent 

    ESTES PARK, Colo. -- At Rocky Mountain National Park in Colorado, rangers are seeing more than green this spring. They're also noticing a little more gray.

    The average visitor to national parks is getting older.

    Cyclist John O'Malley, 61, of Summit County, Colo., has enjoyed the trails for almost half a century.

    "You do get close to nature," Malley said.

    But apparently, not everyone shares that fondness anymore.


    Back in 1996, at Death Valley National Park, almost a third of visitors were in their 20s. But in the last few years, that number has dropped to just 11 percent at Yosemite and six percent at Yellowstone, according to a University of Idaho analysis of Park Service attendance figures.

    At Rocky Mountain National Park, the average age of visitors has risen to 46.  

    "Right now, we see a lot of youth not coming to the parks," said Larry Frederick, a park ranger for more than 15 years who has noticed the changing demographics. "I think there a lot of distractions right now for young people."

    Frederick said the average age of visitors used to be late 20s and early 30s.

    Overall attendance at national parks has dropped only slightly in the last two years. But with fewer young visitors, some conservationists worry about what could happen in the decades to come.

    "If we do not do a better job of inviting young people to the national parks and providing the funding to be able to do that the parks will become less relevant," said Tom Kiernan, president of  the National Parks Conservation Association.

    So the Park Service is mounting a campaign to attract children and young adults -- the Connecting People and Parks program. On a recent Saturday this spring, dozens of kids toured a park outside Washington, D.C. 

    "They get excited [and] they discover things," said Jon Jarvis, the director of the National Park Service. "For them to know that not only they can come back, but they own this place, this is their park."

    The Washington Post / Washington Post/Getty Images

    Nearly 400 national parks can be found all across America, and feature breathtaking vistas, rock formations millions of years old, and more.

    Back in Colorado, the Schafer family from Cleveland, Ohio, is bucking the trend. Three generations chose to enjoy their family vacation this year at a national park. While they are not part of the Park Service's recent outreach program, they fully support it.

    "It's sad to see that the next generation will forget this," Jamie Schafer said, as she looked across a stretch of mountaintops.

    She and her husband drove their kids and grandkids all the way from Ohio. Their goal: to leave their family's computers behind and nurture their love of nature for a lifetime.

    "You can't capture it on a picture," her 12-year-old son, Tobin, said. "You have to be there to see it."

     

  • At least 10 killed in 5.8 magnitude earthquake in Italy

     

    What we're following: 

    - At least 10 killed in Italy earthquake 

    - Number 2 al-Qaeda leader in Afghanistan killed in airstrike

    - Dallas standoff ends as man falls to his death from crane

    And did you see...

    - Metal pieces fall from the sky after Air Canada engine failure

    - Michigan wildfire destroys nearly three dozen homes

    - Tuna carry Fukushima quake radiation across the Pacific

     

     


     

  • The beauty in the details: Idaho's 'Field of Heroes'

    In Pocatello, Idaho, virtually the entire town has been involved in a special Memorial Day celebration. NBC's Mike Taibbi reports.

    By Mike Taibbi, NBC News correspondent

    POCATELLO, Idaho --  I was walking past a hard-used SUV when the passenger window rolled down and a woman’s crooked finger emerged, summoning me over to talk.

    “See that man over there, in the red cap?” she asked. “That’s my husband.  He started all this…” 


    ‘All this.’ As I let my vision follow hers, I saw a vista beneath a morning drizzle of more than 6,000 simple white crosses arranged more or less precisely, filling the entire soccer field behind Pocatello’s Century High School.  The crosses, seized together by a local Korean War veteran and then painted, labeled and tapped carefully into the turf by hundreds of volunteers of every age and interest, were the once-a-year memorial to the fallen in America’s two longest wars, in Iraq and Afghanistan.

    “We have right now 6,378 casualties,” said the man in the cap, who introduced himself as John Rogers.  “Each cross has a label, with the name and unit and casualty date…and if we can keep this going we’re not gonna forget them.”

    I told him his wife Joyce had explained his motivation to meon the day he came home to San Francisco from his war, Vietnam, a “hippie girl” protester had met him as he stepped off the ship and let him know for the first time what his welcome home would be like …  no matter his two Purple Hearts and three tours fighting for his country.

    John nodded.  “She come up to me, she stops and holds up her arms like this…”  He pantomimed carrying an infant.  “And she says, ‘Hey, you baby burner!’

    So in 2004, with the controversial Iraq war a year old and Afghanistan an intensifying warzone following 9/11, he decided to see to it that the veterans fighting and dying in those two conflicts would be treated differently.  He got some fellow veterans to help him find the wood for the crosses and to fabricate simple labels, and talked the town into giving him the use of a piece of land. Then he set up the first “Field of Heroes.”

    It was a simple idea, “sort of like the Vietnam Memorial in Washington,” Rogers said.  A gathering place where each name with identifying details would allow loved ones to reclaim moments of personal connection and remembrance, while permitting strangers who just needed to give thanks a gateway to learn what they choose to learn about the heroes who gave their lives so the rest of us can continue to flourish in ours.

    That first year, there were fewer than 1,400 crosses.  Now, with well over 6,000, there’s almost no more room for additional crosses on Century High’s field;  but the Iraq War is effectively over, and Afghanistan is winding down.

    Mike Taibbi / NBC News

    Iraq war veteran Bruce Marley paints the crosses marking fallen comrades at Pocatello, Idaho's 'Field of Heroes.' Each cross includes the soldier's name, rank, unit, and type of casualty.

    “If we’re lucky, we won’t need this eventually,” Rodgers said.  “But look,” he continued, gesturing. “Now we have people … veterans from Iraq and Afghanistan  they come here and find the special friend they lost over there  they get down on their knees and pray, in front of their crosses.”

    And then there are the loved ones of the fallen: like Tiffany Petty, whose husband Jerrick Petty, with two toddlers back home in Pocatello, volunteered to go to Iraq only to be killed three days after landing.  Tiffany spent several days with the volunteers affixing labels on the crosses of the other war dead, whose service and sacrifice have too often been overlooked by too many.

    “I’ve seen that happen, and it just hurts,” she told me. “It hurts your heart, it hurts your soul  we need to remember these people.”  She looked across the broad field, a thick coil of labels hanging from one wrist.  “And we need to remember them not as a group of people, but as specific people.”

    Prepping for Memorial Day 

    For a few years now, Pocatello’s “Field of Heroes” has been too big a job for John Rogers to handle with just a handful of friends.  Now Bannock County is lending a hand, and whole platoons of volunteers plow into a full week of preparatory work so the field will be ready when the long Memorial Day weekend starts. 

    Mike Taibbi / NBC News

    Pocatello, Idaho's annual memorial, 'Field of Heroes,' honors each of the dead service members who served in Iraq and Afghanistan.

    Scout troops, high school kids, and senior citizens pitch in, alongside strangers who are moved to lend a hand. Big tents with generator-fired heaters warm the volunteers; the local Sign-A-Rama shop makes and donatesthe waterproof labels; and professional surveyors measure the field and line up the rows so the matrix of crosses looks the way it should.  In the middle of the Snake River Plain, in the shadow of the foothills of the Rockies, more than a full brigade of the honored dead appear in silent and precise formation.

    The visitors come from all over the West, bonding over a patriotism that’s as humbling as it is palpable, and understanding each other’s tears.  In fact, there’s nothing like it anywhere in the country, though the feelings generated by a visit to this Pocatello yearly shrine are like those that arise from a famous national shrine:

    “Arlington Cemetery is a long way from here,” said Pocatello Mayor Brian Blad.  “There’s a special spirit there  but you come here, you can feel that same spirit.

    “It’s immense now,” Rogers said, a touch of wistfulness in his voice as he surveyed what his simple idea had turned into.  “But it’s not just a field of crosses…you can come out and read each name…the dates, the places they died…and if you want you can learn their stories.

    It’s important, that we don’t forget the young people we’ve sent to war.

    The old soldier smiled.  “Oh yeah,” he said, pointing to the flags stretched by the breeze on the periphery of the field. Each flag was accompanied by a yellow streamer.  “I still make the printed yellow ribbons for every local soldier coming home.  I’ll keep doing that.

  • Bazell: Calcium critical for bone health, but don't take too much

    A study out Wednesday suggests that calcium supplements might increase the risk for heart attacks. But this research from Swiss scientists in the British journal Heart is just the type of experiment that often scares people unnecessarily and gives the science of epidemiology a bad name.

    The Swiss scientists looked at a group of almost 24,000 people who participated in a European cancer and nutrition study over 11 years. There is the first tip that the research might be less than reliable. The study was set up to look at cancer risk and these scientists are “mining” the data to look for heart disease outcomes. What the researchers unearth is a confusing set of conclusions.  In some people calcium intake seems to protect against heart disease. Indeed in the entire population there was no increase in total heart disease. But among those taking large amounts of supplements, they observe an increased number of heart attacks.

    There has been concern for some time that too much calcium supplementation might cause heart disease because heart disease can result from a buildup of calcium in the arteries.  Several studies of the issue have come to differing conclusions.  What is not in doubt is that calcium in the correct amounts is critical for bone heath, but too much can cause health problems, possibly heart disease but for sure a risk of kidney stones and other health problems.

    The study, though, should remind people that even though calcium is critical for bone health too much can be a hazard.

    As Dr. Ethel Siris of New York-Presbyterian Columbia puts it, "People think more is better in this case in this case more is not better. Enough is enough.”

    Getting the right amount of calcium can be a challenge.  The government recommends that adults take 1000 mg a day of calcium and women over 50 take 1200.  But it says no one over 50 should be taking more than 2000 mg a day.

    It is easy to get too much calcium -- 22 percent of the adult US population takes calcium supplements.

    Many foods have calcium.  A cup of milk, a serving of cheese and a container of yogurt all have more than 300 mg. Some fortified breakfast cereals have as much as 1000 mg per serving.

    But for bone health people do need calcium including a supplement. If they are not getting it from food or other sources they need a supplement – just not too much.

  • 'Boiling point': On Lebanon's Syria Street, a civil war brews

    Syria's chaos has come over the border into Lebanon, with gunmen clashing in deadly street battles. NBC's John Ray reports.

    TRIPOLI, Lebanon – It only takes a two-minute stroll down Syria Street to see why so many people are so worried about what might happen next in Lebanon.

    A hole punched through the wall of the mosque by a rocket or mortar shell, smoke-blackened masonry, shops and apartments bearing the pockmarks of fierce gun battles.


    Syria Street is the aptly named thoroughfare that separates rival factions in Lebanon’s second city.

    For much of the past week, the two sides have been waging a mini-civil war.

    It is a direct spill over from the chaos in neighboring Syria.

    Photos: Violence on the streets of Tripoli

    One side of the street is home to a hard-line Sunni Muslim militia who run guns to rebels across the border.

    “President Assad is trying to destroy us,” says Sheik Bilal Masri, by way of explanation. “They cause trouble here to take the pressure of them in Damascus.”

    Since the Syrian crisis broke out, the price of weapons has exploded in neighboring Lebanon. ITN's John Ray meets the rebels buying the weapons and the dealers selling them.

    We meet a small group of his men. They are well-armed and apparently spoiling for a fight.

    Not many yards away, posters of Syria’s President Bashar Assad striking stern military poses adorn walls on the other side of the street.

    Here the people share Assad’s Alawite faith and, it seems, the same determination to defend his regime.

    Omar Ibrahim / Reuters

    A man hides behind sandbags amid clashes in the Bab al-Tebbaneh neighborhood in Tripoli, Lebanon, on Thursday.

    “No one wants a civil war in Lebanon,” a local Alawite leader tells me.  “But everyone should be warned: There will be repercussion for anyone who tries to meddle in Syria.”

    Conflict along Syria Street is nothing new. But the outside world began to take notice on Monday when for the first time in four years, gun battles broke out on the streets of Lebanon’s capital, Beirut.

    2 killed, 18 hurt as Syria conflict spills over into Lebanon

    It was a brief glimpse back into the abyss for a nation scarred by years of civil strife.

    In 2005, Syrian troops were forced to withdrawal from Lebanon, but Damascus is still a big player in the fractured politics of a country that sees rival Muslim and Christian sects share power in a set of uneasy alliances.

    Syria’s most powerful friend here is Hezbollah, the militant Shiite group that probably holds the key to whether Lebanon survives in one piece.

    Inside Syria rebel stronghold: 'The city is on mute' 

    Its heartland in the south of Beirut has been tense, but so far its leader, Hassan Nasrallah, has kept his forces out of the fray.

    But for how long?

    The fatal shooting of two Sunni clerics followed by the kidnapping of Lebanese Shiite pilgrims in Syria shows how unpredictable events have become.

    A message to Assad? War games held near border

    For more than two decades, Timur Goksel has watched events in Lebanon. Once of the U.N. Mission here, he now lectures at the American University in Beirut.

    He tells me the country has rarely felt so dangerous.

    “I hope I am wrong because this is scary. If the faction leaders lose control of these young guys with the guns then we’re in trouble,” he said.

    Their bloody history has taught the Lebanese to be a fatalistic people.

    “The country is at boiling point,” another seasoned observer told me with a shrug.  “What is coming will be very bad.”

    NBC's Ayman Mohyeldin reports from war-torn Homs showing how parts of the city have been ravaged by fighting while others spared.

     

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  • Deaf baseball player aims for major leagues

    A New Jersey teen who helped lead his team to the state playoffs has been awarded a college baseball scholarship. NBC's Ron Allen reports.

    By Craig Stanley
    NBC News 

    Austin Solecitto is in the middle of a stellar senior year. With the help of his 90 m.p.h. fastball, the left-handed Indian Hills Braves pitcher led his high school baseball team to a 16-6 season and they’re headed to the state playoffs.

    The 18-year-old New Jersey native from Franklin Lakes, N.J., has easily become one of the top pitchers in his region, grabbing the attention of scouts across the nation.

    While his above-average athletic ability is evident, there is something else about Austin that sets him apart from his peers.


    Austin is deaf. He was diagnosed with profound hearing loss at the age of two, after Austin’s parents, John and Gloria Sollecito noticed unusual behavior in their budding toddler.

    “I used to think he just didn’t like me, ‘cause I’d call him and he wouldn’t come,” Austin’s father said. “I said, ‘Something’s wrong.’”

    Before reaching the age of six, Austin had two implant surgeries to mitigate his hearing loss. Since then, Austin has adapted to his disability by picking up ways to enhance his communication skills, including lip reading and hand signals, especially while playing baseball.

    Austin Solecitto says he is a 'typical average high school guy' who enjoys pitching.     

    “You wouldn’t really know he’s deaf,” said John Sollecito. “People think it’s, you know, a radio thing or he’s listening to an iPod. He’s exceeded my expectations as far as what I envisioned it was going to be like when he grew up.”

    Click here to watch the trailer for "I See the Crowd Roar," a documentary about deaf baseball player William Hoy, who played from 1888 to 1902. 

    To compensate for his lack of hearing, Austin wears an external hearing device throughout the day. But it’s not always necessary. Austin says the ability to disable the hearing aid when pitching on the mound has ironically proven to be great advantage on the diamond.

    “When I don't hear anybody -- the other team or the parents -- I can just focus that much easier on just hitting my spots,” he said. The focus pays off – according to ESPN, Austin achieved 67 strikeouts during the 2012 season.  

    That ability to focus, added Austin’s baseball coach George Hill, is an integral part of Austin’s aptitude.

    “I think that is probably his biggest asset -- his composure,” said Hill. “The other team could be yelling, people could be yelling, I could be yelling, and he doesn’t hear you.”

    Austin Solecitto's coach, and his father, describe Austin's extraordinary dedication and focus.

    Austin’s accomplishments on the pitching mound – as well as in the classroom – have paid off. The heavily scouted pitcher, who also maintained a 3.7 GPA this semester, will attend Boston College this fall on a baseball scholarship. These feats come as no surprise to those closest to Austin.

    “He’s been through a lot with his disability,” his brother, Mark, said. “Some things don’t come easy or as easily to him, so I think what that’s taught him is to stick with it and really persevere. I think that’s where he gets his determination from.”

    Austin says he is just doing what comes naturally to him.

    “I kind of think my deafness is overblown,” he said. "To me it’s no big deal, like, I just feel like any other person out there."

    Now Austin hopes to make into a professional baseball league — a mission that both his father and coach support.

    "He's a very special young man,” Hill said. “We'll be watching him and supporting him every step of the way."

     

  • PSA testing guidelines: NBC's Robert Bazell answers readers' questions

    By Robert Bazell, NBC News correspondent

    Your comments on my Monday posting about the task force’s recommendations on PSA testing are greatly appreciated. 

    They were lively, for the most part civilized, and illustrated the complexity of the subject. As the physician in our "Nightly News" report said, “This has been one of the most gut-wrenching aspects of medicine.”

    In response to what many people said I want to repeat that these are recommendations made for the entire population based on what the panel sees as the best evidence.  They are intended to serve as a starting point for a conversation between a man and his physician. They are not an absolute declaration about what any one person should do about his health care.

    To answer some questions that were raised:

    • Some people asked about how the guidelines apply to younger men.  There were no specific recommendations for younger men.  The two big studies of the efficacy of routine testing were done in men in their 50s, 60s and 70s.
    • Some asked about guidelines on what to if prostate cancer is detected.  The task force did not discuss that issue.  The panel certainly made no recommendation against treatment.  But its mandate was to assess the utility of routine screening of healthy men.
    • As for the question of whether prostate cancer is potentially life threatening, despite Gleason scores and other methods for staging prostate cancer, the issue remains difficult.  Much research is being directed at trying to find a molecular marker that would indicate which prostate cancer poses the greatest threat.
    • Others asked why false positives are a bad thing.  False positives -- or in the case of the PSA test even some not-false positives -- can lead to unnecessary treatment, which can have serious side effects.

    Click here to read Robert Bazell's earlier piece about the PSA test guidelines. 


  • Egypt's elections: A struggle between secularism and political Islam -- and how it may transform the Middle East

    AP

    The main candidates, from left: Ahmed Shafiq, Mohammed Mursi, Abdel-Monein Abu al-Fotouh, Amer Moussa and Hamdeen Sabahi.

    CAIRO -- The upcoming Egyptian elections have the potential to not only change Egypt, but the entire Middle East. There’s a strong possibility that decades of American policy in the region can be overturned.  The elections have huge implications for the United States and even bigger ones for Israel.  War and peace may be in the balance. 

    Here in our Cairo bureau as I listen to the boats float by on the Nile blasting music as revelers enjoy the city before it’s clogged by voting with checkpoints, there’s talk that this could be a moment like 1979 in Iran, a possible 180-degree shift for the country and the Middle East.  I’ll start at what’s immediately coming up.

    On Wednesday and Thursday, Egyptians go to polls to elect a new president.  First off, that’s big statement in itself.  Egypt hasn’t elected a truly democratic leader in its 5,000 years of recorded history.  This is the land of the pharaohs, the undisputed and often tyrannical God-kings.  Then it was the land of the Romans, sultans, Mamluks, Khedives, kings, European-dominated governments and finally military rulers. 

    There are five main candidates who have a chance of winning the election.  Egypt has a presidential system.  The president runs the state.  Who the president is matters profoundly.  In no particular order, the candidates are:

    Mohammed Mursi: Mursi is a leading member of the Muslim Brotherhood.  The Muslim Brotherhood, or the Brotherhood for short, is an Islamic group founded in Egypt in 1928.  It has been pursuing a secret campaign to take over the government since its creation.  The Brotherhood wants a state that is modern, powerful, technologically advanced and Islamic.  The Brotherhood is not the Taliban.  It does not want to ban music and pull girls from school, but it does believe that Islam must be the core of politics and society.  The Brotherhood’s slogan has long been “Islam is the solution.”  In practice that means, if there’s poverty, the Brotherhood will look to Islamic principles of helping the poor to solve them.  The Muslim Prophet Mohammed was a big believer in charity and firmly established helping those in need as a basis of the religion. If there’s disease, the Brotherhood sees Islam and its traditions as having a solution to that too.  In questions of war and peace, the Brotherhood will study Islam and its history to determine if a potential conflict is just and warranted.  For the Brotherhood, Islam is always the solution.  It’s Islam uber alles.  The Brotherhood is a politically astute group.  It is calculating and slow moving, believing that the best way to gain power is by gradually winning political and social influence.  The Brotherhood is the grandfather of nearly all Islamic movements.  It is the mothership from which smaller, often more radical groups were born.  Hamas in Gaza, for example, is a faction of the Brotherhood.   The Brotherhood is also rich.  Its finances are murky and secretive.  The group has wealthy donors, especially in the Sunni Arab Gulf states. 

    According to some estimates, the Brotherhood has a million activists in Egypt.  Mursi is the official brotherhood candidate, but would likely end up as the group’s “face man.”  Mursi is not charismatic.  He’s not a dynamic speaker.  He wasn’t the Brotherhood’s first choice.  The group initially wanted its powerful money man Khairat al-Shater, a business tycoon who manages the group’s wealth, to be its candidate, but he was disqualified on account of his prison record.  Egypt’s military-backed presidents, including Hosni Mubarak, imprisoned many Brotherhood members, seeing the group as its biggest existential threat.  Analysts say Shater, the Brotherhood’s supreme guide, and its leadership committee would end up being the real force behind Mursi, pulling the strings. Right after the revolution that toppled Mubarak, the Brotherhood said it would not present a candidate for president, but then broke its promise.  A Brotherhood victory would be a total about-face for Egypt.  Since the late president Anwar Sadat, Egypt has pursued a largely pro-American, Western-leaning policy.  Egypt has maintained a peace treaty with Israel since March 1979, following the Camp David accords.  The Brotherhood has already threatened to cancel the peace treaty if the United States stops providing the $2.1 billion of military and development aid Egypt has received annually since 1982.  The Brotherhood now talks publicly about maintaining good relations with the United States, but at its core the group is not pro-American.  The Brotherhood is actively anti-Israel.  Egypt’s long-term relations with United States and short-term relations with Israel could be at risk if Mursi becomes president.  Egypt is the biggest country in the Middle East.  So goes Egypt, so goes the region.  A dramatic shift in Egypt’s alignment would have global implications.

    Photoblog: Egypt prepares for the post-Mubarak presidential era

    Abdel Monein Abu al-Fotouh.  Al-Fotouh was a member of the Muslm Brotherhood for decades.  He’s a devoted Islamist.  In fact, he was once of member of the even more radical Gamaa Islamiya (Islamic Group), the same organization of Sheikh Omar Abdel Rahman, the blind cleric imprisoned in the United States for masterminding the first attack on New York’s World Trade Center in 1993.  Al-Fotouh left the Gamaa Islamiya for the Brotherhood.  He then broke from the Brotherhood after the Tahrir Square revolution.  The Brotherhood promised at the time not to run a presidential candidate.  Al-Fotouh disagreed and launched his own campaign.  His disobedience to the Brotherhood’s orders infuriated group’s tightly controlled hierarchy and Al-Fotouh was expelled from the Brotherhood.  Since the revolution, Al-Fotouh has been trying to appeal to Egypt’s liberals and secularists.  He says he’s still a member of the Brotherhood at heart, but wants a state where religion doesn’t drive all policy.  It’s possible Al-Fotouh has a change of heart.  Many of the Tahrir Square revolutionaries are taking al-Fotouh at his word.  But is he really different, or just changing his tune to appeal to a broader base?   Al-Fotouh, like Mursi, speaks about maintaining good relations with world powers, including the United States.  During his campaign, however, Al-Fotouh called Israel “an enemy state.”  Al-Fotouh is also now backed by hardline Islamists known as Salafists who want to live in a society modeled on the life of the Prophet Mohammed in the 7th century.  The Salafists – many of them still followers of al-Fotouh’s old group, the Gamaa Islamiya --  want to roll back rights for woman and Christians. Critics say al-Fotouh is trying to be a candidate for everyone, telling revolutionaries and secularists he’s become one of them, while also appealing hardcore Islamists. He has tried to appeal to Christians and women by promising that he will consider appointing one of them vice president should he win. A victory for al-Fotouh would be a win for Islamists.  Is he still member of the Muslim brotherhood in disguise?  Would he make peace with the Brotherhood and return to their fold if he became president?  Al-Fotouh likes to say Turkey is example Egypt could follow with an Islamist leader, but without Islamic fundamentalists deciding how people should live their daily lives.  Critics say its sounds good, but that Egyptian Islamists are much more radical than their Turkish counterparts and that it’s hard to imagine that after decades as a dedicated member of the Brotherhood that al-Fotouh could really have changed fundamentally.  The questions about al-Fotouh’s true beliefs are unlikely to become clear unless he wins the election. 

    Video: A new role for women in post-Mubarak Egypt

     

    Amer Moussa: Moussa is the 76-year-old former Egyptian foreign minister and secretary general of the Cairo-based Arab League.  He is a seasoned and internationally respected statesman.  He’s well known and generally popular in Washington.  Moussa is presenting himself as a steady hand, the candidate who can maintain Egypt’s international relations and not drive the country into isolation or deep into the fold of the Muslim world.  Moussa has said publicly he has no intention of changing or eradicating the Camp David accords with Israel.  He is dedicated to close ties with the United States.  Moussa’s main problem is his association with the former Mubarak regime.  Even though he wasn’t involved in the crackdown and killing of activists during the revolution, he was a key Mubarak associate for decades.  Critics call Moussa part of the “fulool,” a word that meansremnants.”  It is a disparaging term.  It is almost like rubbish or trash.  Critics say Moussa is just another fulool of the Mubarak regime that the revolution swept away.  Moussa’s biggest rivals are the Islamic candidates Mursi and al-Fotouh.  Moussa’s Islamist opponents have tried to depict him as a drinker who is close to Israel and the United StatesMoussa believes Egypt is at a crossroads and that voters can pick him to promote stability or Islamists to change the country’s course in a precarious new direction.

    Ahmed Shafiq: Shafiq is the ultimate “fulool” candidate.  He was the last prime minister appointed by Mubarak.  Shafiq was, like Mubarak, an air force commander.  Shafiq still defends Mubarak.  Shafiq is presenting himself as “Mr. Security.”  After the revolution Egyptian police were discredited.  They were seen as the henchmen of the Mubarak regime.  For the past year, the police have largely been absent from the streets.  With the police gone, murder, rape, kidnappings, car-jackings and antiquities’ theft have all risen dramatically.  Shafiq says he’ll restore order in 24 hours.  He’s the strongman candidate.  His message appeals to some Egyptians fed up with the deteriorating security situation.  Critics say the revolution replaced one dictator in Mubarak and that electing Shafiq would simply be bringing in another one.

    Hamdeen Sabahi.  Hamdeen Sabahi is popularist.  He appeals to the country’s poor.  Economically, Sabahi is a socialist who sees Egypt’s greatest strength as its legions of rural and urban poor.  Politically, Sabahi is a Nasserist, or a follower of the tradition of the late Egyptian president Gamal Abdel Nasser.  Nasser was a champion of Arab unity and a believer in pan-Arab power.  Nasser firmly believed that if Arabs were to unite, they could become a powerful economic and political bloc that could break free of a Middle East many Egyptians see as dominated by American and Israeli interests.  Nasser was no friend of the United States.  He aligned Egypt with the communist Soviet Union and launched a failed war against Israel.  When Nasser died, his successor Anwar Sadat re-orientated Egypt’s economic and politics policies by building close ties with Washington and forging a peace treaty with Israel.  Sabahi’s victory could mean that Egypt’s four-decade-long Western orientation would shift again, reverting to a populist form of pan-Arabism.   Sabahi has had a recent surge in popularity and was recently supported by 400 famous Egyptian actors, artists, writers and journalists.

    On the first anniversary of the uprising that toppled Hosni Mubarak's regime, hundreds of thousands poured into the revolution's symbolic center, Cairo's Tahrir Square. NBC's Ayman Mohyeldin reports.

    The likely outcome
    What’s likely to happen?  None of the five candidates are likely to win an outright majority when voting closes at 8 p.m. Cairo time on Thursday evening.  To win, a candidate needs more than 50 percent of the votes.  It’s widely expected, however, that each of the five leading candidates will win between 10 to 30 percent of the vote.  Mursi for example could win 20-25 percent, Moussa might take another 20 percent, Al-Fotouh perhaps 20 percent and so on.  Since none of the candidates would have the more than the fifty percent needed for a victory, there would be a run-off. 

    The run-off would work as follows:  The two candidates with the highest number of votes -- say Mursi with 25 percent and perhaps Moussa or al-Fotouh or Sabahi with another 20 percent or so – would face each other.  The run-off election would take place on June 16-17.  The winner of the runoff would become Egypt’s next president, starting his four-year term starting on June 30.  Once the new president assumes office, the military council – the leadership committee of generals that has been administering Egypt since the revolution – would dissolve.  Egypt’s first democratically elected president in its history would then run the country and its powerful, US-armed military.

    Who’s winning?
    Opinion polls have been all over the map.  Many polls put Moussa ahead.  The Brotherhood says Mursi is in the lead.  The polls do not seem reliable.  Political analysts I’ve spoken to believe Mursi, even though he’s uncharismatic, is likely to win enough votes to secure a place in the run-off.  After all, the Brotherhood has a million activists get out the vote, a grassroots support base that’s unmatched by any other candidate.  The run-off, according to some analysts, would therefore be between the Brotherhood’s Mursi and someone else.  It’s anyone’s guess who that someone else might be.  That’s when Egyptians’ will have to make an incredibly important choice.  Assuming Mursi is a candidate in the run-off, analysts say the tale of the tape might be like this.

    If the run off is between the Brotherhood’s Mursi vs Amer Moussa or Ahmed Shafiq, analysts predict Mursi would win.  Moussa and Shafiq would simply be too “fulool,” not different enough from Mubarak.  It’s possible, however, the voters could have a change of heart and vote for the promise of stability over the certainty of change.  It’s very hard to predict. 

    If the match up, however, is Mursi vs al-Fotouh or Sabahi, analysts say it’s likely Mursi would lose.  The Brotherhood already controls parliament and voters might fear giving the long-banned group too much power.  Again, no one really knows.  What’s certain is that this is a critical time for Egypt, the Arab world, Israel and the United States.  Egypt is at a crossroads.  The path Egyptians chose is important.  Egypt is the most populous Arab nation, the seat of Sunni Islamic doctrine and has tremendous political, religious and social influence on the rest of the region.  For better or worse, it will lead the rest of the Middle East by example.  So goes Egypt, so goes the region.

    Read more on Egypt from NBC correspondents

     

    More world news from msnbc.com and NBC News:

    Follow us on Twitter: @msnbc_world

     

    Richard Engel is Chief Foreign Correspondent of NBC News

  • FAQ about the new PSA test recommendations

    A federal panel issued a grade of 'D' to the commonly used prostate cancer screening test, concluding that it does more harm than good. But the American Urological Association disagrees. NBC's Robert Bazell reports.

    By Robert Bazell, NBC News correspondent

    Today a federal health panel issued a report stating that routine screening for prostate cancer may lead to more problems for men than it's worth, including over-treatment, complications and side-effects, even as many cancer survivors say the prostate-specific antigen (PSA) blood test saved their lives. 

    For those who want more information on today’s decision, I've posted answers to some of the most frequent questions I've encountered while reporting the story. If you have a question that isn't answered below, ask it in the comment section, or visit my Facebook page. We will accommodate as many questions as possible and post the answers later this week. 


    What is this panel that made the recommendation about the PSA test?

    This answer can be found on the panel’s website: Created in 1984, the U.S. Preventive Services Task Force (USPSTF or Task Force) is an independent group of national experts in prevention and evidence-based medicine that works to improve the health of all Americans by making evidence-based recommendations about clinical preventive services such as screenings, counseling services, or preventive medications. The USPSTF is made up of 16 volunteer members who come from the fields of preventive medicine and primary care, including internal medicine, family medicine, pediatrics, behavioral health, obstetrics/gynecology, and nursing. All members volunteer their time to serve on the USPSTF, and most are practicing clinicians.

    Do the recommendations have the force of law?
    No.  Though the USPTF is financed by the federal government, no federal agency, private insurer, or medical provider is required to follow the recommendations.

    Why did the panel give a 'D' grade to the PSA blood test?
    The panel concluded that on the basis of available evidence, the harms of routine use of the test to detect the possibility of prostate cancer in men outweigh the benefits. It gave the PSA test a 'D' grade.

    What does this mean about my individual medical care?
    The panel and almost all experts say the decision of whether a man should have the test should follow a conversation between the man and his doctor.  The panel’s summary of evidence is intended as a starting point for that conversation.

    How could a test for a common cancer end up being not recommended?
    The heart of that answer is that prostate cancer is very different from other cancers.  In some cases it can be a killer.  But very commonly men have it and it is no threat to their lives.  Doctors have little ability to differentiate between the two kinds.  The panel found that 90 percent of Americans who are diagnosed (more than 240,000 this year) end up being treated with surgery, radiation, hormones or a combination.  The reason for that is that when patients and doctors hear the world “cancer,” they often believe they have a life-threatening illness that must be treated immediately.  But treatment often causes serious side effects, so millions of men have been treated who would have lived long, healthy lives without any treatment.

    But I got a PSA test, then a biopsy and then treatment and I believe the sequence of events saved my life?
    It may be true. Millions believe that, but in most individual cases there is no way to know what would have happened if you did not get treatment. The panel’s conclusions are based on studies of populations, not on individual cases.

    Hasn’t the death rate from prostate cancer fallen since the introduction of the PSA test?
    It has and most experts believe the PSA test has played a big role.  But the questions is whether that drop in the death rate is worth all the men who the statistics show have gotten unnecessary treatment.

    Wouldn’t the solution be for men to get tested and wait to see if they actually need treatment?
    Many experts advocate such an approach which used to be called “watchful waiting” and is now called “active surveillance.”  The problem is that experience has shown that the word “cancer” causes such anxiety that many men will not wait.  Also doctors are often trained to – and benefit financially from – performing procedures.

    More information can be found in the following links to papers published today in the Annals of Internal Medicine.  The first is a summary for patients.  The second is the entire report from the task force.  The third is an article supporting the recommendations.  The fourth is an article opposing them.  

    Summary for patients: http://www.annals.org/content/early/2012/05/21/0003-4819-157-2-201207170-00464.full.pdf+html

    Screening for Prostate Cancer: U.S. Preventive Services Task Force Recommendation Statement: http://www.annals.org/content/early/2012/05/21/0003-4819-157-2-201207170-00459 

    Prostate Cancer Screening: What We Know, Don't Know, and Believe
    http://www.annals.org/content/early/2012/05/21/0003-4819-157-2-201207170-00460 

    What the U.S. Preventive Services Task Force Missed in Its Prostate Cancer Screening Recommendation
    http://www.annals.org/content/early/2012/05/21/0003-4819-157-2-201207170-00463 

     

  • Activists charged with plotting to throw firebombs at NATO summit

     

    What we're following: 

    - 3 activists arrested and charged with plotting to throw firebombs at NATO summit

    - Study finds more than 2,000 people falsely convicted in U.S. since 1989

    - Robin Gibb dies at 62

    And did you see...

    - Nasdaq embarrassed about delays during Facebook debut 

    - President Obama to address Joplin High School graduates 

    - U.S. war veterans return medals at NATO summit

     

     


     

     

  • US agriculture companies pledge millions to Africa

    NBC's Rohit Kachroo visited an irrigation project in Turkana, Kenya, where famine has taken the lives of thousands, and witnessed how it changed the lives of many. Meanwhile, President Barack Obama has announced a plan to boost farm productivity in Africa and alleviate hunger worldwide.

     

    A group of U.S. seed, chemical and equipment companies will invest at least $150 million over the next few years into African agricultural projects and products, the companies said on Friday. 

    The investments pledged by DuPont, Monsanto, Cargill and others are part of an overall $3 billion effort by companies around the world announced by President Barack Obama.

    Along with companies from India, Israel, Switzerland, Norway and the United Kingdom, and 20 companies from Africa, the corporations have committed some $3 billion for projects to help farmers in the developing world build local markets and improve productivity.


    The United Nations has said that by 2030, the world will need at least 50 percent more food, 45 percent more energy and 30 percent more water. Absent these resources, it said, up to 3 billion people would probably be condemned into poverty.

    Capitalizing on food demand in Africa also holds strong profit potential, corporate leaders said.

    "It has been a bit chaotic. There are all sorts of issues around the countries in Africa. But the population, the economic growth, the quality of many of the soils is there," DuPont Executive Vice President Jim Borel told Reuters in an interview. "The need is there, the potential is there."

    USAID's Rajiv Shah explains how 45 businesses will invest in reforming agriculture at the grassroots level to help alleviate hunger in Africa.

    "We're convinced we can take the base we have now, and accelerate that progress," said Borel, who oversees DuPont's food and nutrition businesses. Among DuPont's units is its Pioneer Hi-Bred International seed company, which has operated in Africa for decades.

    India and China are more stable and growing faster, but Africa is "not far behind," according to Borel.

    The push by global corporations to spend more money and develop new markets across Africa comes as an expanding world population and growing demand for quality food threaten to exceed existing limits of agricultural production.

    Investors have been buying up farmland in Africa, hoping to make it more productive using modern agricultural technologies. That, combined with the rising interest of international agricultural corporations, has brought criticism.

    Advocates for African farmers fear they will lose control over their food supply and markets. They say African farmers are being displaced and unsustainable farm practices are being introduced.

    "The problem is all this is based on large-scale commercial agriculture," said Anuradha Mittal, executive director of the Oakland Institute, a policy think tank. "Who does it benefit? All of these things are supporting the formation of large-scale commercial agriculture, which will hurt small farmers. They could spend far less but focus on providing credit facilities, ensuring open markets and ensuring the rights of small holder farmers." 

    More world news from msnbc.com and NBC News:

    Follow us on Twitter: @msnbc_world

     

  • Minorities now surpass whites in U.S. births

     

    What we're following: 

    - Minorities now surpass whites in U.S. births

    - Robert F. Kennedy Jr's estranged wife dead in apparent suicide

    - U.S. Navy ships collide off California coast after a steering malfunction

    And did you see... 

    - First female commander of elite drill sergeant school relieved of duty

    - Pentagon unveils model used to plan bin Laden raid

    - Chicago braces for major protests as NATO summit looms

     

     

  • Lung cancer drug treats rare lymphoma tumors, too

    Doctors at the Children's Hospital of Philadelphia used Xalkori to treat children with anaplastic lymphoma, a disease caused by gene mutation. NBC's Robert Bazell reports.

    By Robert Bazell, NBC News correspondent

    Tonight on "NBC Nightly News" we heard the story of Zach Witt, a vivacious 6-year-old who was close to death from a rare form of lymphoma.  But he was brought back to health by a drug that has been on the market as a treatment for a form of lung cancer.  It truly is a heartening tale.

    The backstory to this achievement shows how progress is being made against certain cancers.  In some ways it is very encouraging. But viewed in other ways, the progress is far slower than many would have predicted.

     


    Before the late 1970s and early 1980s scientists had no idea what happened inside cells to make them cancerous.  Then a series of discoveries revealed that the same genes that control cell growth and division as a fertilized egg becomes a human being can also cause cancer when the growth control genes become mutated.

    Zach Witt's parents, John and Pam, describe Zach's battle against lymphoma and his remarkable recovery.

    After these mutations were discovered the great and obvious hope was that there would be drugs to target them and stop the cancer from growing.  There have been several targeted therapies, but far fewer than anyone expected.  The gene mutation that drives Zach’s tumor, known as ALK, was discovered 25 years ago.  But companies had little interest in developing a drug for that type of cancer –- anaplastic lymphoma -- because it affects only a few hundred children a year in the United States.

    Eventually scientists discovered that ALK is also a driver of about 10 percent of lung cancers.  Lung cancer is so prevalent that even 10 percent makes a substantial market. After extensive testing Pfizer won approval to market Xalkori to treat lung cancer with ALK – at a cost of about $100,000 a year for each patient. The drug works by binding with and inhibiting the action of the enzyme that is produced by the mutated gene.

    And in a study out Wednesday, doctors at the Children’s Hospital of Philadelphia have shown that in eight children Xalkori can very effectively treat Zach’s type of lymphoma. In each child, evidence of cancer disappeared. The research will be presented at the annual meeting of the American Society of Clinical Oncology in June.

    Scientists are decoding the genes of many cancers now, looking for situations like this where, because of a similar gene mutation, a drug already out there -- or combinations of them -- might help other cancers.  But it is going slowly.  The biology is not as simple as one gene mutation causes one cancer. In fact, there can be hundreds of gene mutations contributing to one type of cancer. Many scientists caution against expecting too many spectacular results.

    As Dr. Yael Mosse, Zach’s doctor, put it, “Our goals have shifted. Now we feel that it is more impactful to make a big difference for a small group of patients rather than a small difference for a big group of patients.”

     

  • Should teen football players be tested for Alzheimer's gene?

    Should high school kids get a genetic test for the risk for Alzheimer’s disease before they’re allowed to play football? Two prominent scientists who study both Alzheimer’s and the traumatic brain injury suffered by some football players raise that ethically charged question in an editorial out Wednesday in the journal Science Translational Medicine.

    We all carry a gene called APOE which comes in three forms. If we carry one copy of the form called E4, it triples our lifetime risk for Alzheimer’s. About 10 percent of the U.S. population falls in that category. If we have two copies of E4, the lifetime Alzheimer’s risk is 15 times greater. About 2 percent of us have that genetic makeup.

    Although the connection between APOE E4 and Alzheimer’s risk has been known for years, few have suggested it as a screening tool because there’s no known way to prevent the mind-robbing disease. But, now as scientists want to test drugs as early as possible as potential methods of preventing Alzheimer’s, APOE is getting more attention, as are brain scans and other techniques that might determine who is at risk.

    At the same time, scientists have been finding that football players, boxers and soldiers suffering blast injuries are more likely to develop chronic traumatic encephalopathy (CTE), the form of dementia that can follow a brain injury -- if they have one or two copies of the E4 version of APOE.

    The U.S. government has launched a new website and is pouring millions of dollars into two large studies examining whether or not a drug can slow the progression of Alzheimer's among patients who are predisposed to the devastating disease. NBC's Robert Bazell reports.

    Neurologist Dr. Sam Gandy of Mt. Sinai Medical Center in New York and Alzheimer’s researcher Dr. Steven DeKosky of the University of Virginia School of Medicine, Charlottesville, conducted a poll of 49 colleagues. By a 2 to 1 decision their fellow scientists said it is not yet appropriate to test high school students, and by a 3 to 1 ratio they opposed testing military recruits. But few of the scientists dismissed the ideas out of hand.

    As the evidence of a connection mounts, testing may become more of an imperative.

    There are obvious, enormous ethical difficulties. Telling a 14-year-old that he or she faces an increased lifetime risk of Alzheimer’s could lead to unknowable future strains on individuals and families, as well as a lifetime of difficulty in getting health and life insurance. But if scientists learn how to intervene to prevent the Alzheimer’s, or if the evidence of increased risk from sports or on the battlefield becomes overwhelming, the question may be asked more often.

    Robert Bazell is NBC's chief science and medical correspondent. Follow him on Facebook and on Twitter: @RobertBazellNBC.

    More from Robert Bazell:

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  • NBC's Ayman Mohyeldin answers Syria questions

    Opposition activists said the Syrian security forces opened fire on a funeral procession, killing at least 21 people on Monday. NBC's Ayman Mohyeldin reports from Damascus, Syria.

    Syria has been locked in a violent conflict between President Bashar Assad’s regime and civilian forces for over 14 months. The Assad regime’s crackdown on the popular uprising has left thousands dead and prompted international condemnation.  More than 200 U.N. observers are currently in Syria to monitor a cease-fire agreement which has been repeatedly violated by both sides since it took effect in April.


    Report: Syria rebels get better weapons as US quietly boosts support

    NBC News’ Ayman Mohyeldin is in Syria to report on the latest developments in the ongoing conflict. Ask him your questions during a LIVE Chat beginning at 2:30 p.m. ET. 

    This chat will be moderated. As many questions as possible will be answered. 

  • Anxious Greeks withdraw almost $900 million in one day

     

    What we're following: 

    - Physician says George Zimmerman had broken nose, black eye

    - Anxious Greeks withdraw almost $900 million in one day

    - U.S. has 55 daily encounters with suspected terrorists

    And did you see...

    - FDA delays new sunscreen rules to avoid shortages

    - U.S. veterans to return war medals in protest

    - GM to drop all advertising on Facebook

     

     


     

  • Panetta restricts F-22 flights due to oxygen system complaints

    Defense Secretary Leon Panetta has ordered all F-22 flights to remain near an airfield in case the pilot suffers from oxygen deprivation due to the aircraft's oxygen system. NBC's Brian Williams reports.

    Defense Secretary Leon Panetta has ordered the Air Force to restrict flights of its new F-22 stealth fighters because of continuing problems with the aircraft's oxygen system.

    At least 22 pilots have suffered from oxygen deprivation while in flight since April 2008.

    Panetta on Tuesday ordered that all F-22 flights remain within a "proximate distance" of an airfield in case a pilot should suffer from a hypoxia event and be forced to land. That will force an immediate end to F-22 patrol missions over Alaska.


    Panetta also ordered the Air Force to accelerate installment of a backup oxygen system in all F-22s and provide monthly progress reports on efforts to identify the problem with the current oxygen system.  The Air Force does not expect to begin installing automatic backup oxygen systems until December of this year.

    Watch the Top Videos on msnbc.com

    Handout / U.S. Air Force via Reuters file

    A F-22 Raptor fighter jet flies in a training mission during Red Flag 12-3 over the Nevada Test and Training Range.

    The Air Force has been unable to determine the cause of the 12 incidents of hypoxia suffered by pilots of the F-22. Pilots have reported wooziness while flying the supersonic jet, considered the most advanced fighter plane in the world.

    Some of the military’s top aviators have refused to fly the radar-evading planes because of the oxygen system problems.

    The supersonic plane has also been criticized in the past for its high-maintenance costs. 

    The Air Force reports that each of the aircraft costs $143 million. The U.S. Government Accountability Office, however, estimates that each F-22 cost taxpayers $412 million, if upgrades and research and development expenses are included.

    Jim Miklaszewski is the chief Pentagon correspondent for NBC News. Courtney Kube, NBC's Pentagon producer, and msnbc.com reporter Jeff Black contributed to this report.

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